Idiosyncrasies / by Sir Humphry Rolleston.

  • Humphry Rolleston
Date:
1927
Catalogue details

Licence: In copyright

Credit: Idiosyncrasies / by Sir Humphry Rolleston. Source: Wellcome Collection.

    37/128 page 33
    under the skin or into the spinal canal, and is about 90 per cent, when given intra¬ venously (Coca). It is interesting to note that serum disease is said to be much less frequent in American Indians (46 per cent.) than in whites (90 per cent.). The symptoms are seldom more than troublesome. In the rare instances of sudden death after a first injection of serum, of which Lamson1 in 1924 collected 32 examples, there was probably a sufficient cause, such as asthma with fully developed hypersensitiveness, or, in a few instances,, as in Dr. R. Langerhans’ infant in 1896 to whom he gave a prophylactic injection of anti-diphtheritic serum, the presence of status lymphaticus, in which death may follow any slight cause. Among the rarer manifestations are purpura, haemorrhagic nephritis, colic with melaena,. thus presenting the features of Henoch’s purpura which would appear to be, like angio-neurotic oedema, an anaphylac¬ toid state; polyneuritis with muscular atrophy of which Pollet collected 25 1 Lamson, R. W., Journ. Am. Med. Assoc., Chicago, 1924, lxxxii, 1091. 33 c
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