Two cases of glioma of the retina / by G. E. de Schweinitz and E. A. Shumway.

  • George Edmund de Schweinitz
Date:
[1899]
Catalogue details

Licence: Public Domain Mark

Credit: Two cases of glioma of the retina / by G. E. de Schweinitz and E. A. Shumway. Source: Wellcome Collection.

Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)

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    Convalescence from this operation was uneventful, and the child was dismissed from the hospital about the 15th of August. There is no note that there was any recurrence of the growth at this time. On the 15th of September of the present year the child, after a day or two of great restlessness, was seized with convul- sions and was hurriedly conveyed to the Pennsylvania Hospital. The convulsions ceased very soon, but recurred the same evening, when the child was again taken to this hospital, where he died in a few hours. The note on the book of the hospital is the follow- ing: Unilateral spasms, clonic in character, and coming on in paroxysms ; internal strabismus of the right eye ; twitching of the fingers and toes; rapid, feeble pulse; marked cyanosis ; hurried respiration. Unfortunately an autopsy was not obtained. On interviewing the father as to recurrence in loco, it was ascertained from him that the orbital cavity had healed completely; but that a small button, as he expressed it, was visible at the bottom of the pit. This may or may not have been a recurrence, as it is com- mon to find a small mass of granulation in the orbit after exen- teration, and we are inclined to think that this should be so regarded. The clinical symptoms point to intracranial involvement or metastasis. This is rendered the more likely, inasmuch as the brain, after the cranial and facial bones, is the most frequent region for the appearance of metastatic deposits. The eyeball was placed in a 5 per cent, formalin solution, and subsequently cut in two, one half being mounted in glycerin jelly, and the other embedded in celloidin, and cut in sections parallel to a horizontal plane passing through the cornea and optic nerve. Its anteroposterior diameter measures 26 mm., the vertical 22 mm., and the horizontal 22 mm. The posterior half is filled with a grayish-white mass, which has broken through the sclera, and forms an extraocular nodule, closely investing the optic nerve at its entrance into the ball. The anterior part of the tumor mass stains less well than the posterior. It is composed of a mass of round cells, the majority of which have undergone degeneration, and shows in places dense deposits of lime salts. Certain portions of the growth, especially the better staining ones, show the usual I tubular arrangement which glioma ceils assume : thick mantles ofl well-preserved cells surrounding the bloodvessels and projecting!
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