Licence: Public Domain Mark
Credit: An introduction to pathology and morbid anatomy / by T. Henry Green. Source: Wellcome Collection.
Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.
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![Tlie process commences in the tufts of vessels which form the Malpighian hodies, the walls of which become thickened by the infiltration of the new materia,], so that the tnfts are increased in size. It then proceeds to the small afferent arteries, and ultimately to the vasa effe- rentia, and to the arteriole rectas which run through the medullary portion of the organ. The changes produced in the vessels are very characteristic. Theii'walls are con- siderably thickened and their calibre is so much dimi- nished that the smallest ones cannot be ariifically Fig. 19. Amyloid Degme.ration of a MalivgMan Tuft avd small Arteri/ of the Kidney. Showing tlie thickening of the walls of the vussL'l, the enlargement of the cells of the circular iiuiscukr coat, and the homogeneous layer formed by the intima and longitudinal muscular fibres, x 200, reduced injected. This thickening of the walls of the vessels is mainly owing to alterations in their muscular coat, and especially to the ceils of the circular muscular layer. These cells are much increased in size, they are more or less globular in shape, and many of them have lost their distinctive outlines. The longitudinal muscular fibres and the most internal coat of the vessel are often seen as one homogeneous, glistening, structureless layer. (Fig. 19.)](https://iiif.wellcomecollection.org/image/b21915830_0105.jp2/full/800%2C/0/default.jpg)
