A note upon the relation of traumatic diabetes insipidus to glycosuria / by Herbert French and C. B. Ticehurst.

  • French, Herbert Stanley, 1875-1951.
Date:
1906
Catalogue details

Licence: In copyright

Credit: A note upon the relation of traumatic diabetes insipidus to glycosuria / by Herbert French and C. B. Ticehurst. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

    3/8
    A Note ujxm the Relation of Traumatic Viaheie.^ Following is an nddition to r,ho liistoi’y of that case -L whiclx was published in Vol. LYIf of the (xuifa Hospital Rnports, under the title ‘t A. Uesoarcli upon the Metabolism of a Patient sufFeriug from Diabetes Insipidus, following upon Fracture of the Skull.^’ 'Phe notes of the ca«e at thetimox>f the last publication arc briefly as follows : William T., mt. 44, was in perfect health up to June, 1901. He then met with a bicycle accident, fracturing his basisphenoid. He was unconscious for fourteen days, cerebro-spinal fluid dripping from his nose. He recovered and became active and able to resume work, but suffered from bilateral temporal heinianopia, slight strabismus, polydipsia, and polyuria, all attributable to his head injury. 11 is condition was typical of diabetes insipidus. He Avas under close observation from September 12 to October 15, 1901, during which time all his food and drink were strictly measured and analysed, as wex’e also his nriiie and fxeces. He passed, upon the average, 7500 c.c. of urine daily, of specific gravity 1004. He drank fluid proportionate!}''. The urine Avas daily examined for sugar, but on no occasion could any be found. Not only did the man not pass sugar in his urine Avhen he was taking ordinary diet, but he could not be made to pass sugar Avhen his carbohydrate diet Avas abnormally in- creased. Upon different occasions he Avas given excess of lactose, of grape-sugar, of cane-sugar, and of starch. His daily consumption Avas pushed until he Avas taking over 700 grams of dry carbohydrate in addition to the ordinary amount of proteid and of fat, yet no sugar appeared in his urine at that time. His diabetes insi])idus seemed then to be cpiite free from any tendency to glycosuria. 1’he history of the case subsequent to the metabolic research carried out in 1901 is interesting in that the patient’ has noAv spontaneously dcA^eloped a glycosuria Avhich at that