Lectures on practical medicine and pathology, 1894.

  • Francis Delafield
Date:
1894
Catalogue details

Licence: Public Domain Mark

Credit: Lectures on practical medicine and pathology, 1894. Source: Wellcome Collection.

Provider: This material has been provided by the Augustus C. Long Health Sciences Library at Columbia University and Columbia University Libraries/Information Services, through the Medical Heritage Library. The original may be consulted at the the Augustus C. Long Health Sciences Library at Columbia University and Columbia University.

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    Active congestion is often followed by exudative inflamma- tion. Chronic congestion is often followed by productive in- flammation. Emigration. The escape of the white blood-cells from the capillaries and veins is usually associated with the transudation of blood-serum, but may occur without it. One cause for emigration is the presence in the tissues near the blood-vessels of substances produced by bacteria which are positively chemotactic, that is, of substances which attract white blood-cells toward them. It is also found that a variety of irritating substances in the tissues are capable of causing an emigration of white cells. Ap- parently whenever the emigration of white blood-cells is very large it is due to the presence of pathogenic bacteria, especially the streptococci and staphylococci. The white blood cells which have emigrated into the tissues may remain for a time as pus-cells and afterward degenerate and be absorbed. Or they may change into connective-tissue cells and form permanent new tissue. Furthermore these cells are capable of taking into themselves bacteria and other foreign bodies, and it is probable that in this way they may be of use in limiting infection. It is also to be noticed that when a local emigration of white blood-cells is caused by bacteria there is at the same time an in- crease in the number of white cells in the blood throughout the body—leucocytosis. Production. With or without other inflammatory changes there may be a growth of new tissue. This tissue follows the general type of connective-tissue cells and basement substance. It is known by the names of granulation tissue, round-celled tissue, connective tissue, fibrous tissue, tubercle tissue, etc. As a rule the more acute the process the greater the number of cells; the more clironic the process the greater the quantity of basement sub- stance. In an acute inflammation the production of new tissue may occur by itself, but is more frequently associated with exudation and emisfiation. In chronic inflammations the growth of new
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