Glioma retinae : with report of five cases / by Christian R. Holmes.

  • Christian Rasmus Holmes
Date:
[1902]
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Licence: In copyright

Credit: Glioma retinae : with report of five cases / by Christian R. Holmes. Source: Wellcome Collection.

Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)

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    GLIOMA RETIN/^] WITH REPORT OF FIVE CASES.* CHRISTIAN E. HOLMES, M.D. CINCINNATI, CHllO. Glioma is a disease limited to childhood, and we may consider it the only true neoplasm developing in the retina. Its synonyms are: Neuro-epithelioma'' (Wintersteiner), gliosarcoma (Yirchow), glio-angio- sarcoma and tnbnlar gliosarcoma'' (De Gama Pinto). H. Knapp, in 1867^ appears to have been the first to give an accurate and thoroughly scientific description of this class of tumors. In 1868 appeared Hirschberg's classical work on this subject^ with a report of 77 cases collected from different sources. Virchow believed the cells of this class of tumors to be derived from the sup- porting fibers of the retina (the glia), and hence gave it the name of glioma retinae. Ivvanholf, in 1869, described the structure of the glioma as follows: The larger nodules are always very vascular, with a characteristic arrangement of the cells which are concentrically grouped around the blood ves- sels. On section the whole nodule appears to consist of closely arranged cell rings whose central spaces are filled with red blood corpuscles.'^ Wintcrsteiner has tabulated 500 cases from all sources. 31 of these being his own, which had been very thor- oughly studied microscopically. The same author has tabulated the following cases, in which the origin of the gliomatous growth could positively be traced to one or more of the retinal layers with the following results: * Read at the Fifty-third Annual Meeting of the American Medical Association, in the Section on Ophthalmology, and approved for publication by the Executive Committee : Drs. Frank Allport, IT. V. Wiirdemann and J. A. Lippincott.