The parasite of malaria as observed in the malarial fevers of the south of Spain / by Robert J. Marshall and George Thin.

  • Marshall, Robert J.
Date:
1896
Catalogue details

Licence: Public Domain Mark

Credit: The parasite of malaria as observed in the malarial fevers of the south of Spain / by Robert J. Marshall and George Thin. Source: Wellcome Collection.

    18/54 page 14
    Microscopical appearances in fresh and stained prepara¬ tions.—8.45 p.m. a. Young parasites with a few granules of pigment in the periphery, b. Parasites filling one half or more of the red corpuscles, with peripheral pigment, c. Sterile forms. [The younger forms here correspond to the spores set free on the 22nd, the other and older form to those set free on the 21st.] 24th.—Temperature rose again after midday, reaching 102° at 6 p.m. Ten grains quin, sulph. were given at 2 p.m. Microscopical appearances.-—8.30 a.m. a. Sporulating forms, b. Parasite with peripheral pigment filling about one half to two thirds of red corpuscle, e. Sterile forms. Thus the two generations were again found. 25th.—Attack began after noon, temperature reach¬ ing 101° F. at 4 p.m. Ten grains quin, sulph. were given at 10 a.m., and again at 10 p.m. Microscopical appearances.—9.30 a.m. a. Sporulating forms, b. Sterile forms, c. Pigment-bearing leucocytes. Thus only one generation was found, namely, that causing the fever on the same day, no small parasites of the twenty-fourth attack being seen. Ten grains quin, sulph. were given on the 26th and at intervals afterwards, the patient also taking arsenic in small doses daily. He was discharged well on the 1st June, having had no fever after the 25th. He was seen some time afterwards and was well, continuing to take quinine at intervals. The blood was examined occasionally afterwards and the following appearances noted : 27th.—Two days after last attack. Microscopical appearances.—a. A few sterile forms. b. Two parasites with a very small quantity of pigment. 28th.—a. Sterile forms, b. Two large pheripherally pigmented parasites occupying nearly the whole of the red corpuscle. * c. One small parasite in a red corpuscle with quiescent pigment, probably a dead parasite. 30th.—a. One parasite seen with small quantity of pigment, b. One sterile form.
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