Tissue transplantation into different species / by Leo Loeb and W.H.F. Addison.

  • Leo Loeb
Date:
1908
Catalogue details

Licence: In copyright

Credit: Tissue transplantation into different species / by Leo Loeb and W.H.F. Addison. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    Reprinted from the Society of Philadelphia, TISSUE TRANSPLANTATION INTO DIFFERENT SPECIES. By LEO LOEB and W. H. F. ADDISON. (From the Laboratory of Experimental Pathology and the Anatomical Laboratory, University of Pennsylvania.) The following investigations represent one part of a connected series of researches into the condition of tissue growth.1 Former studies demonstrated the importance of the character of the body fluids for the life and growth of transplanted tissues.2 We expected that a systematic investigation into the transplantation of one kind of tissue of a certain species into a variety of other animal species might throw additional light on the problems of tissue growth. We used for this purpose the skin of the guinea-pig, and carried out series of transplantations into the guinea-pig, the rabbit, dog, pigeo. and frog. Pigmented skin of the guinea-pig ear was used in all cases; it was first thoroughly washed with soap and water, then cleaned with alcohol and bichloride of mercury. The skin was transplanted into pockets in the subcutaneous tissue of the various animals. The pieces were removed after various periods and most of them cut into serial sections. We know of only two investigators who transplanted skin into animals of different species. Beresowsky3 covered defects of the skin 1 Leo Loeb, Beitriige zur Analyse Gewebewachstums I, Arch. f. Entwicklungs- mechanik, 1907, vol. xxiv. 2 Leo Loeb and Samuel Leopold, on the Difference in the Results Obtained after Inoculation of Tumors into the Individual in which the Tumors had Developed, etc., Jour, of Med. Research, vol. xvii, No. 3. 3 Ueber d. Histolog. Vorgange bei der Transplantation von Hautstiicken auf Thiere einer anderen Species, Ziegler’s Bietriige, 1893, Band xii.