Secondary degeneration following unilateral lesions of the cerebral motor cortex / by Sutherland Simpson.
- Sutherland Simpson
- Date:
- 1902
Licence: In copyright
Credit: Secondary degeneration following unilateral lesions of the cerebral motor cortex / by Sutherland Simpson. Source: Wellcome Collection.
Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.
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![matter of tlie optic thalamus in tlie outer or lateral half of which the}' appear to terminate/ and there is a considerable amount of fine degeneration in this region of the thalamus. The internal capsule on the opposite side is quite free from degeneration as also is the grey matter of the optic thalamus of that side. In sections taken more posteriorly through the subthalamic region the same fine degeneration is seen in the grey matter on the left side with fibres passing into it from the internal capsule. In the upper levels of the mesencephalon the left crusta shows extensive degeneration which does not involve its lateral and mesial extremities. Several detached bundles of degenerated fibres, cut trans- versely, seem to be passing dowiwards in the substantia nigra lying behind the left crusta, and there is a slight amount of fine degene- ration scattered amongst the grey matter of the substantia nigra. No fibres can be made out passing backAvards into the tegmentum, as was the case in most of the cats examined. No fine degeneration is visible in the central grey matter or in that of the anterior corpora quadrigemina. In sections through the upper, middle, and loAver levels of the pons the pyramidal bundles on the left side are extensively degener- ated, and all around these, but more especially on the mesial and antero-lateral aspects, there is very abundant fine degeneration amongst the cells of the nuclei pontis. Tliis fine degeneration is exceedingly Avell marked in the dog (figs. 7 and 8. pi. XVI). In the medulla oblongata above the pyramidal decussation, as in the cat, a feAV fibres are seen to leave the posterior aspect of the degenerated pyramid; some cros- sing the median raphe are soon lost amongst the internal arcuate fibres of the opposite side, while a very few disappear in the for- matio reticularis of the same side. In sections through the pyrami- dal decussation crossed (heterolateral) and uncrossed (homolateral) bund- les come off from the degenerated pyramid and curve backAvards and outwards through the central gi-ey matter tOAvards the lateral columns of the opposite and of the same side respectively, to take up a. ])osi- tion con'esi)onding to that of the lateral colunni iu the spinal cord. The homolateral fibres are only seen in small fasciculi in sections](https://iiif.wellcomecollection.org/image/b21455727_0017.jp2/full/800%2C/0/default.jpg)
