Secondary degeneration following unilateral lesions of the cerebral motor cortex / by Sutherland Simpson.
- Sutherland Simpson
- Date:
- 1902
Licence: In copyright
Credit: Secondary degeneration following unilateral lesions of the cerebral motor cortex / by Sutherland Simpson. Source: Wellcome Collection.
Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.
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![relationship between the motor and sensory paralysis on the affected side of the body, and tliat therefore the motor cortex cannot be the sole seat of tactile sensation as advocated by Munk [7], Mott [8] and others, but that this must be sought for in some other part of the cortex. The transient sensory disturbances that often follow motor cortical lesions, may, as pointed out by Schafer [5], be due to slight unavoidable injury to other parts of the hemisphere, or to altered vascular conditions produced by the operation, and when these con- ditions return to the normal the sensory paralysis passes off while the motor remains. They may, however, have a more far reaching cause as is shown by the fact that they are often accompanied by hemi- anopsia. This has been recorded by Mott [4], and by Ferrier and Turner [9], and has recently been emphasized by Hitzig [10]. 2. Anatomical. Briefly stated, as a result of complete left motor cortical lesions in the cat, dog and monkey, in addition to degene- ration of the main pyramidal tract in the internal capsule, crusta, pyramidal bundles of pons, and anterior pyramid in the medulla ob- longata on the left side, and in the crossed pyramidal tract of the spinal cord on the right side, fine or terminal degeneration was pre- sent in the optic thalamus, substantia nigra, grey matter of the ante- rior corpus quadrigeminum and of the nuclei pontis on the left side, and in the grey matter at the base of the posterior horn in the cer- vical and lumbar enlargements of the spinal cord on the right side. A few fibres could be traced from the degenerated tract into the optic thalamus and substantia nigra, and numerous fibres were found to pass from the degenerated crusta to the anterior corpus quadri- geminum of the same side where they appear to end, while a few cross the. middle line in the rOof of the aqueduct to the anterior corpus of the opposite side. These fibres to the ant. corp. quad, were only found in the cat. No degenerated fibres could be made out passing to any of the cranial motor nuclei and no fine degeneration was found in these nuclei or in any portion of the central grey matter around the Sylvian aqueduct, or in the floor of the 4*^ ventricle. In the medulla oblongata above the crossing of the pyramids a few fibres could be traced from the degenerated pyramid for a short distance](https://iiif.wellcomecollection.org/image/b21455727_0023.jp2/full/800%2C/0/default.jpg)
