Determination of radicles in carbon compounds / by Dr. H. Meyer. Authorized translation by J. Bishop Tingle.

  • Meyer, Hans (Hans Johannes Leopold), 1871-
Date:
1903
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Licence: In copyright

Credit: Determination of radicles in carbon compounds / by Dr. H. Meyer. Authorized translation by J. Bishop Tingle. Source: Wellcome Collection.

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    Zinc dihydroxylaviine Jiydrochloridc, ZnCl2.2NH2OI I, has beeil used chiefly for tlie preparation of ketoximes1 as its resolution into Hydroxylamine and anhydrous zinc chloride facilitates the elimination of water. It is pre- pared2 by adding zinc oxide (i part) to hydroxylamine hydrochloride (2 parts) in boiling alcoholic solution. The boiling is continued in a reflux apparatus for a few moments, and the liquid allowed to cool. The com- pound is deposited as a crystalline powder which dis- solves sparingly in water or alcohol, but readily in Solu- tions of hydroxylamine hydrochloride. Ortho- and paraquinones, and metadiketones do not react with hydroxylamine if several atoms of Hydro- gen in the ortho-position are replaced by halo'id atoms or alkyl groups.3 Aromatic ketones of the formula (CH3.C)2C.COR, where R = phenyl or an alcohol I radicle, are also, incapable of forming oximes;4 indeed, the presence of carbonyl, which does not yield oximes, in such compounds as acids,5 amides,6 or esters7 may, by the production of hydroxamic acids, lead to errone- ous results. The Statement that alkyl salicylates and hydroxylamine give salicylhydroxamic acid7 has been confirmed.8 The unsaturated ketoalcohol camphor- oxalic acid. C-.C.OH.CO.'OH C„H,.< 1 1 Crismer, Bull. soc. cliim. [3], 3, 114. a ß 23) r 223. 3 Kehrmann, Ibid. 21, 3315 Herzig and Zeisel, lind. 21, 3494. Cf. Ibid 22, 1344. 4 V. Meyer, Ibid. 29, 836. Feit and Davies, Ibid 24, 3546, Biginelli, Gazz. 24, /, 437. Claus, J. pr. 45, 383. Baum, B. 28, 3209. 6 Nef, Ann. 258, 282. 6 C. Hoffmann, B. 22, 2854.