Determination of radicles in carbon compounds / by Dr. H. Meyer. Authorized translation by J. Bishop Tingle.

  • Meyer, Hans (Hans Johannes Leopold), 1871-
Date:
1903
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Licence: In copyright

Credit: Determination of radicles in carbon compounds / by Dr. H. Meyer. Authorized translation by J. Bishop Tingle. Source: Wellcome Collection.

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    high temperature in a sealecl tube with hydrochloric acid, are all converted into amides by continued boil- ing with alcoholic potassium hydroxide.1 The amide is hydrolysed to the acid in the manner described in the following section. Cyanmesitylene 2 requires boiling during seventy-two hours with alcoholic potassium hy- droxide, and triphenylacetonitrile3 needs fifty hours boiling with the same reagent to produce the amide. Some nitriles that are otherwise resistant may be hy- drolysed by heating at I20°-I30° during an hour with 90 per Cent sulphuric acid (20-30 parts). The resulting amide is converted into the acid by means of nitrous acid 4 (cf. following section). Unhydrolysable nitriles have also been described.5 6 (e) Certain amides may be obtained by the action of alkaline hydrogen peroxide at 40°® on the nitriles; the resulting compounds are then treated in the manner described on p. 111. (/) Some nitriles may be reduced to the correspond- ing amine by means of zinc and hydrochloric acid7 or sodium and alcohol.8 DETERMINATION OF THE AMIDO GROUP (CO.NH2). The amido group is determined by hydrolysis, in a similar manner to the nitrile group (preceding section). 1 Bouveault, S. p. So. Hantzsch and Lucas, B. 28, 748. 2 V. Meyer and Erb, Ibid. 29, 834. 8 V. Meyer, Und. 28, 2782. 1 Sudborough, Jour. Cliem. Soc. 67, 601. Münch. B. 29, 64. 8 J. Deinert, J. pr. 52, [2] (1895), 431- Radziszewsky, B. 7, 18, 355. J. K. Auwers and A. J. Walker, Ibid. 31 (1899), 3044. 6 Claus and Wallbaum, J. pr. 56, 52.