The Lumleian lectures on some moot point in the pathology and clinical history of pneumonia : delivered before the Royal College of Physicians of London on May 30th and June 4th and 6th, 1912 / by Percy Kidd.
- Kidd, Percy
- Date:
- [1912]
Licence: In copyright
Credit: The Lumleian lectures on some moot point in the pathology and clinical history of pneumonia : delivered before the Royal College of Physicians of London on May 30th and June 4th and 6th, 1912 / by Percy Kidd. Source: Wellcome Collection.
Provider: This material has been provided by London School of Hygiene & Tropical Medicine Library & Archives Service. The original may be consulted at London School of Hygiene & Tropical Medicine Library & Archives Service.
35/82 page 31
![torated is sero-albuminous fluid, representing plasma whose fibrinogen has been precipitated to form fibrin, mixed with hyaline mucus and certain cells. With respect to the chemistry of hepatized lung, De Jong recalls some experiments of Sotnischewsky [5], a pupil of Hoppe Seyler, who found that watery extracts of red hepatized lung yielded an albuminoid substance that coagulated at a temperature of 540 C, a substance allied to myosin and fibrinogen. This substance could not be obtained from lung in the stage of grey hepatization or from healthy lung. Watery extracts from the two latter coagulated at a temperature of 60-700 C, like certain well-known albuminoids. De Jong suggests that the special albuminoid of red hepatization represents the sero-albuminous fluid found in the sputum in the early stages of pneumonia. The cause of the adhesiveness of the sputum was studied by Kossel [6]. According to his observations pneumonic sputum contains more nuclein than tuber- culous sputum. But although nuclein in solution pos- sesses a consistency and adhesiveness analogous to that of pneumonic sputum, Kossel did not venture to make a positive assertion on this topic. Sahli [7] says that pneumonic sputum is usually very viscid on account of the nuclein it contains. De Jong disagrees with this view, and holds that viscidity of the sputum depends on the thick hyaline variety of mucus. With regard to the presence of mucin in the sputum, Wanner [8], in opposition to the statements of Renk, finds that pneumonic sputum contains a considerable quantity of this substance, more than is found in tuber- culous cases. The same author separated albumin from the other constituents of the sputum and estimated its quantity at different stages. Albumin is very abundant in the early days of pneumonia, but its amount diminishes with the progress of the disease. In order to test the value of a bacteriological exami- nation of the sputum, Dr. Paul Fildes, assistant bacteri-](https://iiif.wellcomecollection.org/image/b21353487_0035.jp2/full/800%2C/0/default.jpg)
