London Vaccine Institution: for inoculating and supplying matter free of expense. : Patronized by His Majesty's ministers, members of both houses of Parliament, the Hon. the East India Company, and the Corporation of the City of London. Eseablished [sic] in 1806, and supported by voluntary contributions.

  • London Vaccine Institution
Date:
1822
Catalogue details

Licence: Public Domain Mark

Credit: London Vaccine Institution: for inoculating and supplying matter free of expense. : Patronized by His Majesty's ministers, members of both houses of Parliament, the Hon. the East India Company, and the Corporation of the City of London. Eseablished [sic] in 1806, and supported by voluntary contributions. Source: Wellcome Collection.

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    DESCRIPTION of the VACCINE POCK. In vaccination, a redness at the place of puncture, or incision, lakes place in a da;, or two; a little pimple then arises, which map be felt with the finger, or be distinctly seen; this gradually increases till the tenth dap, when it appears about the size of a pea, considerably depressed on its summit, elevated at its cir- cumference, with an areola, or circumscribed inflammation, about the size of half a crown, surrounding the pock. If at this time the circulation be quickened by heat or exercise, or if by grasping the arm the skin at the inflamed part be put upon the stretch, there is an appearance of throbbing in the areola, or inflamed part, arising from the pulsations of the neighbouring arteries. After this, the centre dries and hardens, taking on the appearance of a dark brown crust or scab, which insensibly is extended throughout its substance ; and in about three weeks', from the time of the inoculation, the crust or scab falls off, in shape and colour resembling a tamarind stone, leaving an eschar or cicatrix CcicatricleJ often in- delible or permanent through future life. CRITERION of PROTECTION. If, from any kind of accident, the pock be broken, or if the matter have been taken from it in such quantity as to destroy its ordinary appearance, the inflam- mation and induration always accompanying or constituting the areola, yields the certain proof of the subject being perfectly protected. At this period a symp- tomatic fever, however transient, is uliuays felt by the patient.—J. VV. Director of the Loud Vacc. Inst. “ The efflorescence at the inoculated part, which seldom supervenes before the eighth or later than the eleventh day, is to be regarded as an indi- cation that the whole system is affected.—YVoodville, London. “ Lc seul symptome essentiellement necessairc, est la tumeur produile par le virus d la place de l'inoculation.—Aubert, a Paris. “The appearance of the areola is a decided proof that the antivariolous change has been produced in the system ; and, independent of this circum- stance, I know no means by which the practitioner can be assured that the true disease has taken place”—De Carro, Vienna. “ In some of the darkcr-eomplexioned Asiatics, the areola is not so obvious to the eye as in European patients, on account of the different opacity of the rete mucosum of the skin; but the hand applied to the circumference of the vesicle, readily discovers the firm hardness iu them as well as in Europeans.”—Anderson, Madras. EXTRANEOUS ERUPTIONS NOT PRODUCIBLE. Can extraneous humours be inoculated together with the Cowpock ? No; nor yet with the Smallpox. By the violence of the latter disease, the constitution may be so injured, that latent tendencies (technically, predisposing causes) may be aggravated, and the patient thus become a victim to disease, which, without the previous shock of Smallpox, he might have altogether escaped. Vaccination and Variolation are works so distinct, that, begun, carried on, and completed in the constitution, they admit not any other disease to mingle ivith them. They can only shew themselves near relatives to each other. While they uniformly arrest, during their presence, other diseases, as scarlatina, measles, fyc. they exist some- times and go on together, each diminishing the effect of its sister disease. From such subject, the inoculator can take matter by applying his lancet to the one or the other pock, and this will produce only the one distinct disease which he makes choice of—]. VV.