Leprosy in its clinical & pathological aspects / by G. Armauer Hansen and Carl Looft ; translated by Norman Walker.

  • Gerhard Armauer Hansen
Date:
1895
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Licence: Public Domain Mark

Credit: Leprosy in its clinical & pathological aspects / by G. Armauer Hansen and Carl Looft ; translated by Norman Walker. Source: Wellcome Collection.

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    ferent, that it is impossible to confuse them, and the microscopical differences are still more evi- dent. Both fresh and hardened preparations were always examined. And since the lymph glands are always affected with leprosy, if the organs which drain into them are affected, even if this affection is very slightly developed, we conclude from the fact that we have never seen a leprous bronchial or mesenteric gland, that there is no leprous affection of the lungs or of the intestine, and later examination of certain special preparations have only confirmed us in this view. But more of this later, and we will first treat of the differences between tuberculosis and leprosy. In organs affected with tubercle one always finds, as is well known, giant cells and caseous degeneration ; in the many, we can truthfully say, thousands of preparations of leprous affections, which we have had under the microscope, we have never seen either a typical giant cell with marginal nuclei or caseous degeneration. There are indeed multinuclear cells in the lepromata, but never giant cells like those of tubercle. What may be the reason for this striking dif- ference in the action of the very similar bacilli of tubercle and leprosy, we have no idea ; we simply state the fact and assert that, if one finds giant cells, he is dealing with tuberculosis and not with leprosy. This alone would be sufficient
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