Chloroform : a manual for students and practitioners / by Edward Lawrie.

  • Lawrie, Edward.
Date:
1901
Catalogue details

Licence: In copyright

Credit: Chloroform : a manual for students and practitioners / by Edward Lawrie. Source: Wellcome Collection.

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    which no longer lowers the blood pressure or pro- duces anaesthesia. The most important point connected with the physiology of the fall of the blood pressure under chloroform is its cause. The Hyderabad Commission was unable to prove more than that a fall of the blood pressure is not in itself dangerous ; conse- quently the fall which is invariably produced by chloroform when effectively given by inhalation cannot be due to failure of the heart. The precise cause was subsequently determined by Professor Gaskell’s and Dr. Shore’s cross-circulation experiments, by means of which, when a cross-circulation is estab- lished between two animals, the chloroform can be sent at will either (a) to the heart alone, or (b) to the brain alone. When chloroform is sent to the heart alone it produces no effect : it has no direct action on the heart. When it is sent to the brain alone its usual action is exhibited, viz., lowering of the blood pressure, with, first insensibility, then anaesthesia, then stoppage of the respiration, and then