Lead poisoning in its acute and chronic forms : the Goulstonian lectures, delivered in the Royal College of Physicians, March 1891 / by Thomas Oliver.
- Date:
- 1891
Licence: Public Domain Mark
Credit: Lead poisoning in its acute and chronic forms : the Goulstonian lectures, delivered in the Royal College of Physicians, March 1891 / by Thomas Oliver. Source: Wellcome Collection.
Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.
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![according to Iicrnstein, along the niesenteric artery. T agree with lliegel that colic, high arterial tension, and retarded action ot‘ the lieart, are all present together. Are they coincident ? The high arterial tension oidy lasts at iirst during the colic, hence the absence in the early stages of lead poisoning of the hypertrophy of tlie heart which is noticed in the later stages. It is dillicult to separate, in point of tiinc, the three states, colic, high tension, and slowed action of heart, but it seems to me as if lead first irritated the sympathetic and intestinal ganglia; this is followed by spasm of portions of intestine and arteries, and by inhibited heart s action. That such is the course of events is contirnied by a consideration of the functions of the kidney. During lead colic, very little urine is secreted. In some of my own cases there has been suppression of urine, or from 6 to 12 ounces of urine only have been secreted daily. AVherever there was severe colic, and heightened arterial tension, just in proportion was the amount of urinary secretion dimin- ished, and corres])ondingly its specific gravity increased. The interesting puint observed in my cases is this, that after an interval of freedom from pain which had been accompanied by high tension, and its attendant deficiency of urination, when the colic had returned days after, arterial tension again rose, and the same deficiency was observed in the amount of iirinJ secreted. The facts here enunciated were also observed bv 'I';!/}, llit'l'Uii.'jcd. liccoiiic I'oiisidi'nililv](https://iiif.wellcomecollection.org/image/b21921507_0071.jp2/full/800%2C/0/default.jpg)
