Dr. Pereira's Elements of materia medica and therapeutics : abridged and adapted for the use of medical and pharmaceutical practitioners and students and comprising all the medicines of the British Pharmacopœia, with such others as are frequently ordered in prescriptions or required by the physician / edited by Robert Bentley and Theophilus Redwood ; with an appendix.
- Jonathan Pereira
- Date:
- 1874
Licence: Public Domain Mark
Credit: Dr. Pereira's Elements of materia medica and therapeutics : abridged and adapted for the use of medical and pharmaceutical practitioners and students and comprising all the medicines of the British Pharmacopœia, with such others as are frequently ordered in prescriptions or required by the physician / edited by Robert Bentley and Theophilus Redwood ; with an appendix. Source: Wellcome Collection.
1115/1180 (page 1083)
![get a product equal to the weight of the phosphorus used. The remainder goes to the formation of phosphate of lime, of which the quantity produced may be even more than this statement represents if the temperature be allowed to rise near to the boiling point of water. The other hypophosphites are usually prepared from this, as in the following case:— [§ Sodae Hypophosphis. Hypoghosphite of Soda. Na03PO,2HO or NaPH202, Obtained by adding carbonate of soda to solution of hypophos- phite of lime as long as a precipitate of carbonate of lime is formed, then filtering the solution and evaporating it to dryness by the heat of a steam-bath, keeping it constantly stirred when the salt begins to solidify. Characters and Tests.—A white granular salt having a bitter nauseous taste. It is deliquescent, very soluble in water and in spirit, but insoluble in ether. At a red heat it ignites, emitting spontaneously inflammable phosphuretted hydrogen. Dose.—2 to 5 grains.] For the therapeutic effects of the hypophosphites see page 213. [§ Chloral Hydras. Hydrate of Chloral. C4HC1302,2H0 or C2HC130.H20. Chloral, produced by the action of dry chlorine gas on anhydrous alcohol, purified by treatment, first with sulphuric acid and after- wards with a small quantity of lime, and finally converted into the solid hydrate by the addition of water. Characters and Tests.—In colourless crystals, which do not deliquesce on exposure to air. It has a pungent but not an acrid odour, and a pungent and rather bitter taste. On the application of a gentle heat it fuses to a colourless transparent liquid, which, as it cools, begins to solidify at a temperature of about 120°. It boils in a test-tube, with pieces of broken glass immersed in it, at about 205°, and at a slightly higher temperature it volati- lises on platinum foil without residue. Soluble in less than its own weight of distilled water, rectified spirit, or ether, and in four times its weight of chloroform. The aqueous solution is neutral or but slightly acid to test-paper. A solution in chloroform when mixed by agitation with sulphuric acid does not impart colour to the acid. 100 grains of hydrate of chloral dissolved in an ounce of distilled water and mixed with 30 grains of slaked lime, submitted [3 *J](https://iiif.wellcomecollection.org/image/b20392357_1115.jp2/full/800%2C/0/default.jpg)