Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS.
    

concept

The Lhx-7 gene in the oral mesenchyme

Hoxa-2 in situ hybridisation in chick embryo

The Barx-1 gene in the embryonic head

Guidebook to the homeobox genes / edited by Denis Duboule.

Master control genes in development and evolution : the homeobox story / Walter J. Gehring.

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Genes, Homeobox

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Hoxa-2 in situ hybridisation in chick embryo

Guidebook to the homeobox genes / edited by Denis Duboule.

The Barx-1 gene in the embryonic head

Master control genes in development and evolution : the homeobox story / Walter J. Gehring.

The Barx-1 gene in the embryonic head