Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
    

concept

Tobacco (Nicotiana sp.): flowering stem with separate leaf. Coloured etching by M. Bouchard, 1772.

Smoking tobacco (Nicotiana tabacum L.): flowering and fruiting stem. Coloured etching by M. Bouchard, 1772.

Tobacco plants (Nicotiana rustica and N. paniculata): flowering and fruiting stem of both species with their respective floral segments.Engraving by J.Caldwall, c.1805, after P.Henderson.

An occasional paper of the British Anti-Tobacco Society / by Wm. Hardwicke ... embracing the recent researches of M. Jolly on tobacco smoking in France.

A voice from Hawaii / by T.S. Southwick.

Effect of tobacco smoking on the nervous system / by Sir Humphry Rolleston, Bart., K.C.B., Physician in ordinary to His majesty the King ; Regius Professor of physic in the University of Cambridge.

Nicotine

Images

Catalogue

An occasional paper of the British Anti-Tobacco Society / by Wm. Hardwicke ... embracing the recent researches of M. Jolly on tobacco smoking in France.

A voice from Hawaii / by T.S. Southwick.

Effect of tobacco smoking on the nervous system / by Sir Humphry Rolleston, Bart., K.C.B., Physician in ordinary to His majesty the King ; Regius Professor of physic in the University of Cambridge.

The tobacco question : physiologically, chemically, botanically, and statistically considered / [William E.A. Axon].

The cigarette papers / Stanton A. Glantz [and others] ; foreword by C. Everett Koop.