An autosomal dominant disorder caused by deletion of the proximal long arm of the paternal chromosome 15 (15q11-q13) or by inheritance of both of the pair of chromosomes 15 from the mother (UNIPARENTAL DISOMY) which are imprinted (GENETIC IMPRINTING) and hence silenced. Clinical manifestations include MENTAL RETARDATION; MUSCULAR HYPOTONIA; HYPERPHAGIA; OBESITY; short stature; HYPOGONADISM; STRABISMUS; and HYPERSOMNOLENCE. (Menkes, Textbook of Child Neurology, 5th ed, p229)
    

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Prader Willi & Angelman syndromes - FISH

Growing babies. Part 1, War in the womb.

Can't stop eating.

The ghost in your genes.

To be different is all right too : Prader-Willi's syndrome.

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Prader-Willi Syndrome

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Growing babies. Part 1, War in the womb.

Can't stop eating.

Prader Willi & Angelman syndromes - FISH

The ghost in your genes.

To be different is all right too : Prader-Willi's syndrome.