A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
    

concept

Meeting the challenge of disabling disease : animal research brings hope / Research for Health Charities Group.

Datura stramonium (Thornapple). Also called Jimsonweed

Inside the brain / Wellcome Trust.

Parkinson Disease

Images

Catalogue

Parkinson's disease / Richard West.

An essay on the shaking palsy / by James Parkinson.

Parkinsonism.

Antiparkinsoniano Diparcol : lo que hay que saber del: Diparcol ... / marcas Rhône Poulenc Specia.

With shaking hands : aging with Parkinson's disease in America's heartland / Samantha Solimeo.