A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
    

concept

The head of a man with goitre. Etching by Jusepe de Ribera, 1622.

Three wild born people, all with goitre. Engraving, 1787.

Nagaland, India: Ao Nagas tribespeople, one of whom is suffering from a goitre. Photograph, 1900/1910.

A man with goitre. Chalk drawing by J. de Ribera.

The thyroid gland / editors: Rosalind Pitt-Rivers [and] W.R. Trotter.

Stop the thyroid madness. II : how thyroid experts are challenging ineffective treatments and improving the lives of patients / Janie A. Bowthorpe, editor.

Be your own thyroid advocate : when you're sick and tired of being sick and tired / Rachel Hill.

[Endocrine tumours and disturbances]

Solved : the riddle of illness / Stephen E. Langer and James F. Scheer.

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Hypothyroidism

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The thyroid gland / editors: Rosalind Pitt-Rivers [and] W.R. Trotter.

Stop the thyroid madness. II : how thyroid experts are challenging ineffective treatments and improving the lives of patients / Janie A. Bowthorpe, editor.

Be your own thyroid advocate : when you're sick and tired of being sick and tired / Rachel Hill.

[Endocrine tumours and disturbances]

Solved : the riddle of illness / Stephen E. Langer and James F. Scheer.