A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
    

concept

'Migril' masters migraine : even master minds can be slaves to migraine.

'Migril' masters migraine : whatever the situation 'Migril' masters migraine.

'Migril' masters migraine : a first!.

Theine in the treatment of neuralgia : being a physiological contribution to the therapeutics of pain / by Thomas J. Mays.

Fluscorbin : Vitamin C + quinine massive dose : attack treatment of colds and influenza.

Coffee and caffeine / by Rolf Ulrich ; translated by Janet Ellingham.

Affirmative chemical action / by Thomas Szasz.

This is your mind on plants : opium - caffeine - mescaline / Michael Pollan.

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Theine in the treatment of neuralgia : being a physiological contribution to the therapeutics of pain / by Thomas J. Mays.

Fluscorbin : Vitamin C + quinine massive dose : attack treatment of colds and influenza.

Coffee and caffeine / by Rolf Ulrich ; translated by Janet Ellingham.

Affirmative chemical action / by Thomas Szasz.

This is your mind on plants : opium - caffeine - mescaline / Michael Pollan.