A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).
    

concept

Graves Disease

Catalogue

The thyroid gland / editors: Rosalind Pitt-Rivers [and] W.R. Trotter.

An unusual case of Graves' disease / by James Craig.

Oedema in Graves' disease / by Arthur Maude.

The value of diminished electrical resistance of the human body as a symptom in Graves' disease / by H.W.D. Cardew.

The present status of the surgery of systematic goitre : illustrative cases / William Seaman Bainbridge, A.M., Sc.D., M.D.