A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
    

concept

Venetian drug bottle c.1700 : a study in pharmaceutical elegance / Distillers Company (Biochemicals) Limited.

Safe sedation 'Distaval' 25 mg. thalidomide per tablet... : 'Distaval' Forte 100 mg. thalidomide per tablet ... sounder sleep / The Distillers Company (Biochemicals) Limited.

Deformities caused by thalidomide.

Thalidomide kid / by Kate Rigby.

Bioethics in historical perspective / Sarah Ferber.

Thalidomide plus 25.

Broken promises.

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Thalidomide

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Deformities caused by thalidomide.

Thalidomide kid / by Kate Rigby.

Bioethics in historical perspective / Sarah Ferber.

Thalidomide plus 25.

Broken promises.