A mixture of PICROTOXININ and PICROTIN that is a noncompetitive antagonist at GABA-A receptors acting as a convulsant. Picrotoxin blocks the GAMMA-AMINOBUTYRIC ACID-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates.
    

concept

K voprosu o potoostanavlivaiushchikh sredstvakh u chakhotochnykh : agaritsin, pilokarpin, gomotropin, diubuazin i pikrotoksin : dissertatsii na stepen' doktora meditsiny / Semena Abletsova.

Picrotoxin

Catalogue

K voprosu o potoostanavlivaiushchikh sredstvakh u chakhotochnykh : agaritsin, pilokarpin, gomotropin, diubuazin i pikrotoksin : dissertatsii na stepen' doktora meditsiny / Semena Abletsova.