Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.
    

concept

Cosmid DNA probe for chromosome 9, human

Use of DNA probe on c-some 9 heterochromatin

DNA probe for Y chromosome, meta/interphase

The calculation of genetic risks : worked examples in DNA diagnostics / Peter J. Bridge.

Current Japanese research on biosensors, DNA probes, DNA biosensors and gene sequencing / Tom Salusbury and Yasuko Otsuka.

Recombinant DNA technology : concepts and biomedical applications / Mark Steinberg [and others].

Galleries and Reading Room

Library

Shop

Café

Please note, our Changing Places toilet is currently out of service and undergoing repair works.

We're running paid user research studies to improve Wellcome Collection online

Take part in research

DNA Probes

Images

Catalogue

The calculation of genetic risks : worked examples in DNA diagnostics / Peter J. Bridge.

Current Japanese research on biosensors, DNA probes, DNA biosensors and gene sequencing / Tom Salusbury and Yasuko Otsuka.

Use of DNA probe on c-some 9 heterochromatin

Recombinant DNA technology : concepts and biomedical applications / Mark Steinberg [and others].

Cosmid DNA probe for chromosome 9, human