Successful canine infection with cultures of Leishmania infantum (C. Nicolle) / F.G. Novy.

  • Frederick George Novy
Date:
1908]
Catalogue details

Licence: Public Domain Mark

Credit: Successful canine infection with cultures of Leishmania infantum (C. Nicolle) / F.G. Novy. Source: Wellcome Collection.

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    PRELIMINARY NOTE. In May, 1903, Major Leishman described peculiar chromatin bodies which he found in the spleen of a patient suffering from the so-called dum-dum fever of Calcutta, and at the time he suggested the possibility of these having a trypanosomal origin. This observation was soon confirmed by Donovan and others, and conse- quently the so-called Leishman-Donovan bodies have come to be recognized as the cause of Kala-azar or trop- ical splenomegaly. In December of the same year J. H. Wright gave an accurate description of similar bodies found in the le- sions of Delhi boil or Oriental sore, and like results were obtained about the same time by Marzinowsky. While, morphologically, the Wright bodies are identical with those of Leishman, there is good reason to believe that they represent distinct though related organisms. A third infection of similar type was recognized by Pianese, in Naples, in 1905. In five out of twelve cases of infantile splenic anemia he found intracellular bodies - which resembled those of Leishman. The recent study | of this disease of infants by C. Nicolle, director of the 4 ites Pasteur Institute of Tunis, are of commanding interest tte tence in view of the results achieved. The organisms referred to may be placed, for the pres- ent at least, in the genus Leishmania created by Ross. They are known, therefore, as: *Hrom the Hygienic Laboratory, University of Michigan, This investigation has been aided by a grant from the Rockefeller Insti- tute for Medical Research. WELLCOM® INSTITUTE LIBRARY we! TROMeC_ cal| pane pare Eos MONONA x 2220014728
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