Two cases of acute general psoriasis following vaccination / by George H. Rohé.

  • George Henry Rohé
Date:
[1882]
Catalogue details

Licence: Public Domain Mark

Credit: Two cases of acute general psoriasis following vaccination / by George H. Rohé. Source: Wellcome Collection.

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    TWO CASES. OF ACUTE GENERAL PSORIASIS FOLLOWING VAC¬ CINATION.1 BY GEORGE H. ROHE, M.D., Professor of Hygiene and Clinical Dermatology, Gollege of Physicians and Surgeons, Baltimore. THE occurrence of general eruptions after yaccination has been noted so frequently of late that the thought of impurity of the virus must have presented itself to many. Dr. Henry A. Martin has, however, recently shown2 that such eruptions had been very often noticed shortly after the introduction of the practice of vaccination, and that, since the more fre¬ quent use of animal virus, these eruptions complicated the manifestations of the vaccine disease in a much larger proportion of cases. Dr. Martin quotes Willan, who speaks in a work on vaccine inoculation, published in 1806, “ of a profuse and general miliary eruption as being noticed about once in fifty cases of vaccinia in the human subject,” and from his own experience, corroborates very exactly Willan’s approximative esti¬ mate of its frequency. The general roseolar eruption, whether diffused or occurring in spots or larger patches, supervenes sufficiently often that nearly every one having much to do with vaccination must have noticed examples. Behrend3 also speaks of urticarias, exudative erythemas, and eczematous eruptions as complications of the vaccine disease. A case of the latter (acute general eczema), apparently lighted up by the vaccina¬ tion, recently came under my notice. The so-called “gangrenous vac¬ cinia” which I cannot believe to have any relation with true vaccinia at all, but which I imagine to result from the inoculation of septic or decom¬ posing matter, and which produces an ulcer, sometimes destroying all the tissues down to the bone, has been so frequently noticed during the past winter and spring that no extended reference to it is necessary. Opportunity has not been afforded me to make an extended search into the literature of the subject, but I have hitherto seen no cases re¬ ported that bore any resemblance to two which have been lately under my care, and which I venture to briefly put on record. Case I.—J. W. 0., a physician, 28 years of age, consulted me in February, 1882, with the following history: 1 Read at the sixth annual meeting of the American Dermatological Associa- t on, at Newport, R. I., August 80, 1882. 2 N. Y. Med. Record, April 15, 1882. 3 Archives of Dermatology, Oct., 1881.
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