Duchenne muscular dystrophy deletion, FISH

Human chromosomes highlighted by fluorescent probes which bind to specific sequences of DNA. The FISH (fluorescence in situ hybridisation) study is of a female heterozygous for a deletion in the Duchenne muscular dystrophy (DMD) gene. The DMD cosmid probe is red, the X chromosome centromeres are green. See B0000325C for control. Image by Dr John Crolla.