Researches on the nature of enzyme-action. I, On the causes of the rise in electrical conductivity under the action of trypsin / by W.M. Bayliss.
- William Bayliss
- Date:
- [1907?]
Licence: Public Domain Mark
Credit: Researches on the nature of enzyme-action. I, On the causes of the rise in electrical conductivity under the action of trypsin / by W.M. Bayliss. Source: Wellcome Collection.
1/32
![[Reprinted from the Journal of Physiology, Vol. XXXVI. No. 4.] RESEARCHES ON THE NATURE OF ENZYME-ACTION. I. On the causes of the Rise in electrical conductivity under the action of Trypsin. By W. M. BAYLISS. (From the Physiological Laboratory of University College, London.) CONTENTS. PAGE Introductory F ; : ‘ F : é ; : tip 22d The change in viscosity . 3 ‘ : : : : . 223 The increase of inorganic ions . ‘ ; ‘ ; : a. 2ol The production of ‘“‘peptones” . ; : : : : . 235 The production of amino-acids . . : : ; é it 239 Some properties of amino-acids: i, Solubility of mixtures . ‘ : ; : F . 246 ii. Electrical conductivity of certain of their salts. . 247 iii, Carbamino-acids . ; : ; . ‘ ; . 250 Summary of conclusions . , ‘ ; : F ‘ wi 725% Introductory. The first investigator who made experimental use of the change in electrical conductivity shown by various solutions under the action of enzymes was Sjégvist'. He found that the hydrolysis of albumins by pepsin was accompanied by a diminution of conductivity. This fact was confirmed by Oker-Blom?, who also observed that the action of trypsin was accompanied by a rise in conductivity and advocated the method as of great convenience in the study of the action of various proteolytic enzymes. It has been employed for this purpose by Victor Henri and Larguier des Bancels?, who have published a few experiments chiefly on the Jaw of action of trypsin on gelatin. I have myself carried out a large number of experiments for the most part on trypsin, a preliminary account of which will be found in the Arch. des Sciences Biologiques, X1. Supp. p. 261, St Petersburg, 1904. 1 Skand. Arch. f. Physiol. v. p. 364. 1895. 2 Versamm. Nordischer Naturf. in Helsingfors, Verh. d. Sektion f. Anat. u. Physiol. p.. 9. 1902. 3 C. R. Société de Biol. pp. 563 and 787. 1903. PH. XXXVI. 15 4834o.](https://iiif.wellcomecollection.org/image/b33448097_0001.jp2/full/800%2C/0/default.jpg)
