Immunisation against blackleg and braxy / T. Dalling.

  • Dalling, Thomas.
Date:
[1925?]
Catalogue details

Licence: In copyright

Credit: Immunisation against blackleg and braxy / T. Dalling. Source: Wellcome Collection.

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    Reprinted from The Journal of Pathology and Vol. XXVIII., 1925, p. 536. Bacteriology, 1 is IMMUNISATION AGAINST BLACKLEG AND BBAXY. T. Dalling, M.R.C.V.S. Wellcome Physiological Research Laboratories, Beckenham, Kent. It was shown by Allen and Bosworth (Vet. Journ., 1924, vol. lxxx., p. 9) that with a culture filtrate of B. chauvei and a mixture of V. septique toxin and anti¬ toxin it was possible to immunise laboratory animals and sheep against infection 3y both organisms. Since one or other (or both) of these organisms almost certainly causes all “ blackleg 5' of cattle and sheep and braxy in sheep, the use of this louble prophylactic promised to give protection against several diseases much [eared by stock owners. Sheep were immunised by Allen and Bosworth and rre still at the Wellcome Physiological Research Laboratories. Some of them have recently, 18 months after the injection of the vaccine, been given intra¬ muscular injections of lethal doses of culture of the two organisms and have successfully withstood the test. The immunity is thus, as one would expect, }f reasonably long duration. During the past winter, nine farmers used the prophylactic on approximately half of the sheep on each farm. 549 sheep were inoculated and 464 kept on the same farms and under the same conditions were kept as controls with no inocu¬ lation. Of the inoculated group 2 (0'36 per cent.) died of braxy, of the non- moculated 72 (15‘5 per cent.) died. It is reasonable to conclude that the prophylactic has given a high degree of protection against braxy. Field trials :>f the prophylactic in blackleg areas are in progress. PRINTED BY OLIVER AND BOYD, EDINBURGH
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