An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
    

concept

Cocaine : gay men, sex and drugs / Terrence Higgins Trust.

Kelene (Κ́ηλ́ε or I calm) : pure chloride of ethyl, local anaesthetic in glass tubes.

Hall's Coca Wine : the elixir of life / Stephen Smith & Co. Ltd.

Serum antidiphterique (Roux-Behring System) : prepared by Doctor Villejean.

The "Allenburys" throat-pastilles : efficient and palatable : February 1910.

Coca myths : drugs and democracy programme / authors Anthony Henman, Pien Metaal ; ed. Martin Jelsma and others.

Cocaine / by Walter H. Jessop.

Alberta Alcoholism and Drug Abuse Commission (AADAC) (part 1)

DAWN (Drugs Alcohol Women Nationally)

Drugs. (1), Cocaine, crack, heroin, LSD / TACADE.

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Coca myths : drugs and democracy programme / authors Anthony Henman, Pien Metaal ; ed. Martin Jelsma and others.

Cocaine / by Walter H. Jessop.

Alberta Alcoholism and Drug Abuse Commission (AADAC) (part 1)

DAWN (Drugs Alcohol Women Nationally)

Drugs. (1), Cocaine, crack, heroin, LSD / TACADE.