An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
    

concept

Duchenne muscular dystrophy patient and carrier.

Muscular Dystrophy, Duchenne

Catalogue

Duchenne muscular dystrophy patient and carrier.

M0014499: Progressive muscular atrophy: front view / M0014500: Progressive muscular atrophy: rear view

Duchenne muscular dystrophy patient and carrier.