Immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat

concept

Cellular architecture of normal human skin imaged by whole mount tissue microscopy. Human skin has a rich network of white blood cells (specifically dendritic cells, T cells and macrophages) which form sheaths around blood vessels. In this image, T cells (stained for CD3; red) dendritic cells (stained for MHC class II; green) and macrophages (stained for LYVE-1; blue with some cells showing a tinge of green) can be seen. Cell nuclei have been stained with DAPI (grey). This normal cellular architecture is grossly disrupted in diseased skin (see related images). X10 magnification. Scale bar (white) represents 200 micrometres.

Toxic shock syndrome toxin

Human macrophage rupturing after infection with Chlamydia

Staphylococcal enterotoxin A

Cellular architecture of normal human skin imaged by whole mount tissue microscopy. Human skin has a rich network of white blood cells (specifically dendritic cells, T cells and macrophages) which form sheaths around blood vessels. In this image, blood vessels (string-like structures stained for CD31; red), lymphatic vessels (ribbon-like structures stained for LYVE-1; blue) and dendritic cells (stained for CD11c; green) can be seen. Macrophages (stained for LYVE-1; blue) are also present. This normal cellular architecture is grossly disrupted in diseased skin (see related images). X10 magnification. Scale bar (white) represents 200 micrometres.

Cellular architecture of normal human skin imaged by whole mount tissue microscopy. Human skin has a rich network of white blood cells (specifically dendritic cells, T cells and macrophages) which form sheaths around blood vessels (string-like structures). A network of lymphatic vessels (ribbon-like structures) is also present. In this image, human skin lymphatic vessels (stained for LYVE-1; blue) and white blood cells comprised of dendritic cells (stained for CD11c; green) and T cells (stained for CD3; red) can be seen. Some macrophages also express the protein LYVE-1 similar to lymphatic vessel cells which can be appreciated as blue cells within and in between the sheaths of white blood cells. This normal cellular architecture is grossly disrupted in diseased skin (see related images). X10 magnification. Scale bar (white) represents 200 micrometres.

Streptococcal pyrogenic exotoxin A1

Mast cell granules - scroll-type

Trichuris muris is a parasitic nematode affecting mice. Following ingestion, T. muris eggs hatch in the large intestine where they develop into adults. The anterior end of the worm burrows into the lining of the gut, leaving the posterior end protruding into the lumen of the gut. The worms mate in this orientation, and the resulting eggs are released in to the gut lumen and shed faecally. 

Cells interacting to cause immune response

Cellular architecture of normal human skin imaged by whole mount tissue microscopy. Human skin has a rich network of white blood cells (specifically dendritic cells, T cells and macrophages) which form sheaths around blood vessels. This image was taken less than 20 micrometres beneath the junction that joins the dermal and epidermal layers of the skin (dermo-epidermal junction). At this level, dendritic cells (stained for CD11c; green) form clusters around and between blood capillary loops (stained for CD31; red). The blind-ended tips of initial lymphatic vessels are just visible (stained for LYVE-1; blue) at this level. This normal cellular architecture is grossly disrupted in diseased skin (see related images). Scale bar (white) represents 200 micrometres.

Cellular architecture of human skin lymphoma imaged by whole mount tissue microscopy. Normal human skin has a rich network of white blood cells (specifically dendritic cells, T cells and macrophages) which form sheaths around blood vessels. In diseased skin, such as in skin lymphoma as seen here, this normal architecture becomes distorted. In this image, lots of T cells (stained for CD3; red), dendritic cells (stained for CD11c; green) and macrophages (stained for LYVE-1; blue) have infiltrated the skin. X20 magnification. Scale bar (white) represents 100 micrometres.

Eosinophil-derived neurotoxin

Invertebrate immunity : mechanisms of invertebrate vector-parasite relations / edited by Karl Maramorosch, Robert E. Shope.

Staphylococcal enterotoxin C2

Galleries and Reading Room

Library

Shop

Café

We're experiencing some technical problems in the library today. 

If you’re visiting us, you won’t be able to print or use our PCs or laptops. If you want to sign-up for a free library membership, we’ll give you a temporary card for today and complete your membership next time you visit.

You can access items from the collection as usual and our team is on hand to help. Thank you for your patience while we resolve these issues. 

We're running paid user research studies to improve Wellcome Collection online

Take part in research

Immune response

Images from the collections

Images referencing Immune response

Works from the collections

Eosinophil-derived neurotoxin

Invertebrate immunity : mechanisms of invertebrate vector-parasite relations / edited by Karl Maramorosch, Robert E. Shope.

Streptococcal pyrogenic exotoxin A1

Staphylococcal enterotoxin C2

Immune response

Images from the collections

Images referencing Immune response

Works from the collections

Eosinophil-derived neurotoxin

Invertebrate immunity : mechanisms of invertebrate vector-parasite relations / edited by Karl Maramorosch, Robert E. Shope.

Streptococcal pyrogenic exotoxin A1

Staphylococcal enterotoxin C2

Related topics